Children can get cancer in the same body parts as adults, but childhood cancers appear suddenly and without early symptoms. Children’s immature immune system allows the red flags cancer to stay dormant, for longer periods. However, Children have generally have a high cure rate, but childhood cancers such as leukemia, lymphoma and brain tumours are still the second leading cause of death for children ages 1-14.
The body’s immune system fights off sickness, but cancer is good at hiding from our immune system. NFCR is working on a technique that gives the body’s cancer-fighting cells a way to find the cancer, so it can then fight it.
NFCR scientists have found microRNAs that can suppress the development of leukemia and increase the rate of normal blood cell growth. To pave the way for new treatments, we are researching how these microRNAs work.
We are conducting clinical trials for a drug that shuts down the growth part of giloblastomas, a very aggressive type of brain tumour.
NFCR is researching a new treatment for soft tissue sarcomas that cannot be handled with surgery. A protein in the cancer moves to healthy cells and makes them ready for the cancer to come. We are trying to identify what the protein is attracted to so that we could apply treatments to fend the protein off.
To treat bone cancer, drugs are used to target the growth of the cancer, but there are many different combinations of drugs and they need to match the cancer to be effective. NFCR is using a computer program to match the correct drug combination to the cancer, reducing the time and costs of developing treatments.